Elucidating host cell response pathways and repurposing therapeutics for SARS-CoV-2 and other coronavirusesArticle Published on 2022-11-052022-11-15 Journal: Scientific Reports [Category] SARS, 신약개발, 치료제, [키워드] Analysis common cold Coronaviruses Compound COVID-19 COVID-19 therapeutics cytotoxicity effective gene expression profile globe Heat shock homoharringtonine host cell response host response in silico in vitro modulating other coronavirus pandemic pathway Prevent provided reported SARS-CoV-2 SARS-CoV-2 biology screened severe symptoms tanespimycin target tested unique Vaccine viral infection [DOI] 10.1038/s41598-022-21984-w PMC 바로가기
SARS‐CoV‐2 infection remodels the host protein thermal stability landscapeSARS-CoV-2 감염은 숙주 단백질 열 안정성 풍경을 개조합니다Article Published on 2021-02-162022-09-10 Journal: Molecular Systems Biology [Category] MERS, 치료제, [키워드] abundance acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition alteration aryl hydrocarbon hydroxylase biosafety Cell cell cycle cellular cellular processe cellular processes change changes in condition coronavirus displaying effective framework global change handling Health heat shock chaperone Host host protein host proteins human pathogen imperative Infection Interaction Microbiology, Virology & Host Pathogen Interaction microtubule molecular Pathogens Protein proteome provide Regulation Replication respiratory rhapontigenin RNA splicing SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 severe acute respiratory syndrome Coronavirus stability suppressed tanespimycin targets therapy thermal thermal stability Vaccine [DOI] 10.15252/msb.202010188 PMC 바로가기 [Article Type] Article